Interleukin-10 Promoter Polymorphism in Psoriasis
نویسندگان
چکیده
منابع مشابه
Interleukin-10 promoter polymorphism in psoriasis.
Beneficial effects of interleukin-10 therapy and lower endogenous interleukin-10 formation compared with atopic dermatitis and cutaneous T cell lymphomas indicated that interleukin-10 is a key cytokine in psoriasis. The interleukin-10 promoter is highly polymorphic, with two informative microsatellites, interleukin-10.G and interleukin-10.R. In order to understand whether interleukin-10 itself ...
متن کاملevaluation of interleukin-10 (g-1082a) promoter polymorphism in preeclampsia
background: preeclampsia is a pregnancy-specific syndrome that may be life-threatening, especially to the fetus. several causes have been reported that may have a possible role in the development of the disorder. interleukin-10 affect maternal intravascular inflammation, as well as endothelial dysfunction. the aim of this study was to investigate the association between il-10 g-1082a polymorphi...
متن کاملEvaluation of Interleukin-10 (G-1082A) Promoter Polymorphism in Preeclampsia
BACKGROUND Preeclampsia is a pregnancy-specific syndrome that may be life-threatening, especially to the fetus. Several causes have been reported that may have a possible role in the development of the disorder. Interleukin-10 affect maternal intravascular inflammation, as well as endothelial dysfunction. The aim of this study was to investigate the association between IL-10 G-1082A polymorphis...
متن کاملInterleukin-10 gene promoter polymorphism and risk of liver cirrhosis.
We conducted a hospital-based case-control study to assess the association between IL-10-592 A/C, IL-10-819 C/T, and IL-10-1082 A/G polymorphisms and the risk of liver cirrhosis in a Chinese population. This 1:1-matched case-control study included 192 patients from the Chinese PLA General Hospital. Genotypes of IL-10-592 A/C, IL-10-819 C/T, and IL-10-1082 A/G were detected by polymerase chain r...
متن کاملInterleukin-10 Promoter Polymorphisms and Breast Cancer Risk in Iranian Women
Background: IL-10 is an anti-inflammatory cytokine which is involved in tumorigenesis. Over production of IL-10 and elevated number of IL-10 generating mononuclear cells in breast tumor tissue has already been shown. Objective: To determine the association of IL-10 promoter polymorphisms with increased risk of breast cancer and its association with breast cancer prognostic factors. Methods: Per...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2001
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.2001.01350.x